Clinical Application and Dosage of Angelicae Sinensis Radix in the Treatment of Dryness Syndrome

¹ Key Laboratory of Dryness Syndrome of Traditional Chinese Medicine, Ministry of Education, Ningxia Medical University, Yinchuan 750004, Ningxia, China

² College of Traditional Chinese Medicine, Ningxia Medical University, Yinchuan 750004, Ningxia, China

AMCMR 2026 , 2(3), 24–31; https://doi.org/10.61369/AMCMR.2026S1003

(This article belongs to the Special Issue Commonly Used Traditional Chinese Medicines for Treating Dryness in Clinical Practice)

© 2026 by the Author. Licensee Art and Technology, USA. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution -Noncommercial 4.0 International License (CC BY-NC 4.0) ( https://creativecommons.org/licenses/by-nc/4.0/ )

Abstract

A review of classical medical texts and the clinical experience of physicians was conducted to summarize the dosage and compatibility patterns of Angelicae Sinensis Radix in the treatment of dryness syndrome. Its dosage ranges from 9 to 41.4 g in decoctions and from 0.16 to 1.94 g per dose in boiled powders and related preparations. Dosage and compatibility should be individualized according to the disease, syndrome pattern, and clinical manifestations. For constipation due to blood deficiency and body-fluid depletion, Angelicae Sinensis Radix is commonly combined with Cistanches Herba, Cannabis Fructus, Persicae Semen, and Pruni Semen to nourish blood, moisten the intestines, and promote bowel movement, at a decoction dosage of 9–30 g. For blood-dryness dermatoses, including psoriasis and pruritus in older adults, it is commonly combined with Rehmanniae Radix, Chuanxiong Rhizoma, and Paeoniae Radix Rubra to nourish blood, moisten dryness, and dispel wind, at 10–15 g. For perimenopausal syndromes, it is commonly combined with Astragali Radix, Paeoniae Radix Alba, and Leonuri Herba to tonify and harmonize blood, at 9–15 g. For dryness impediment (Zao Bi) and Sjögren’s syndrome, it is commonly combined with Rehmanniae Radix Praeparata, Rehmanniae Radix, and Ophiopogonis Radix to nourish Yin and moisten dryness, at 12–20 g.

Keywords

Angelicae Sinensis Radix

Dose-effect relationship

Compatibility

Clinical application

Funding

Basic and Clinical Research Innovation Team for Target-Oriented Syndrome Differentiation and Treatment of Type 2 Diabetes Mellitus with Traditional Chinese Medicine in Ningxia Hui Autonomous Region (Project No. 2022BSB03113)

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